Within the POND Network, there are many different studies that explore neurodevelopmental disorders in ways that have never been done before. The aim is to increase our understanding of the underlying biology of these neurodevelopmental disorders, how they are similar, different and connected, and how this knowledge can be used to improve clinical and community care.
General recruitment for the POND study is open. Please contact the POND site nearest you for more information.
POND Clinical Trials Network
The POND clinical trials network is an alliance of several Ontario clinical research centres with expertise in neurodevelopmental disorders. These groups are cooperating in the design and conduct of clinical trials whose goals are to predict and describe the shared biology and response to treatment of children with neurodevelopmental disorders, such as ASD, ADHD, ID, and OCD.
A randomized placebo-controlled trial of ARBaclofen vs. placebo in the treatment of children and adolescents with ASD – “The ARBA” Study
We are currently investigating a study drug called arbaclofen to improve social functioning in children and teens with Autism. This study is comparing arbaclofen against placebo for improving social & global function and communication.
POND Longitudinal Sub-Study: Understanding how neurodevelopmental disorders change or remain the same over time.
The POND Network is collecting information and doing research studies to understand how genes, brains and bodies are different if a person has Autism Spectrum Disorder (ASD) or Attention Deficit Hyperactivity Disorder (ADHD) or Obsessive Compulsive Disorder (OCD) or Intellectual Disability or Fragile X or Rett Syndrome or Tourette Syndrome or Down Syndrome or who are typically developing. The reason we are doing this is to find better ways to help people with disorders who may want treatment. The information we collect and the studies we will do are part of a large effort from the Ontario government to fund research in disorders that affect the brain (Ontario Brain Institute). This is a sub-study of the Province of Ontario Neurodevelopmental Disorders (POND) study.
A pilot study of an antioxidant cocktail vs. placebo in the treatment of children and adolescents with Rett syndrome.
Please contact the POND site nearest you for more information.