Mouse and Cell Models of Neurodevelopmental Disorders

Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Portman T, Yang M, Mao R, Panagiotakos G, Ellegood J, Dolen G, et al. Cell Reports 7:1077-1092. 2014.

Behavioral and neuroanatomical phenotypes in mouse models of autism. Ellegood J, Crawley JN. Neurotherapeutics. 2015 Jul;12(3):521-33.

Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Ellegood J, Anagnostou E, Babineau BA, Crawley JN, Lin L, Genestine M, et al. Molecular Psychiatry. 1-8. 2014.

Developmental expression of neuroligins and neurexins in Fragile x mice. Lai JKY, Doering LC, Foster JA. J Comp Neurol. 524:807-828. 2015.

Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Horev G, Ellegood J, Lerch JP, Son Y-EE, Muthuswamy L, et al. Proc Natl Acad Sci USA. 2011: 11; 108(41): 17076-81.

Genetic effects on cerebellar structure across mouse models of autism using a magnetic resonance imaging atlas. Steadman PE, Ellegood J, Szulc KU, Turnbull DH, Joyner AL, Hendelman RM, Lerch JP. Autism Research 7(1):124-37. 2014.

High resolution whole brain imaging of anatomical variation in XO, XX, and XY mice. Raznahan A, Probst F, Palmert MR, Giedd JN, Lerch JP. Neuroimage 83: 962-968. 2013.

Loss of T cells influences sex differences in behavior and brain structure. Rilett KC, Friedel M, Ellegood J, MacKenzie RN, Lerch JP, Foster JA. Brain, Behavior, and Immunity. 46: 249-260. 2015.

Neuroanatomical assessment of the integrin ß3 mouse model related to autism and the serotonin system using high resolution MRI. Ellegood J, Henkelman RM, Lerch JP. Frontiers in Psychiatry 3: article 37. April, 2012.

Neuroanatomical analysis of the BTBR mouse model of autism using magnetic resonance imaging and diffusion tensor imaging. Ellegood J, Babineau BA, Henkelman RM, Lerch JP, Crawley JN. Neuroimage 70: 288-300. 2013.

Neuroanatomical phenotypes are consistent with autism-like behavioral phenotypes in the 15q11-13 duplication mouse model. Ellegood J, Nakai N, Nakatani J, Henkelman M, Takumi T, Lerch J. Autism Research 8(5):545-55.  2015.

Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion. Ellegood J, Markx S, Lerch JP, Steadman PE, et al. Molecular Psychiatry 19: 99-107. 2014.

Regional brain volumes changes in adult male FMRI-KO mouse on the FVB strain. Lai.JKY, Lerch JP, Doering LC, Foster JA, Ellegood J. Neuroscience. March 24; 318-:12-21. 2016.

Temporal and spectral differences in ultrasonic vocalization in fmr1-/- mice during postnatal development.
Lai, JKY, Sobala-Drozdowski M, Zhou L, Doering LC, Faure PA, and JA Foster. Curr Opin Biotch 32:35-41. 2014.

T-lymphocytes and anxiety: a review of clinical and animal studies. Rillett KC, Foster JA. Ann Depress Anxiety. 1(7):1034. 2014.