Rett syndrome is a neurodevelopmental disorder that affects girls almost exclusively. Children with this condition appear to grow and develop normally in their early years. They then have a slowing of their development. Other symptoms include an inability to use their hands to make deliberate movements, and wringing or clapping their hands. Children with Rett also have slowed brain and head growth. Later, they will have trouble walking and will develop seizures. There is almost always a degree of intellectual disability. Many children also have autism-like behaviours. The severity of all of the symptoms varies.
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